In order to meet the needs of enhanced oil recovery in low-permeability reservoir，a new type of nanoemulsion was developed as an oil-displacing agent. Its interfacial property，wettability，temperature and salt resistance were evaluated. The oil displacement efficiency of the nanoemulsion oil-displacing agent was investigated by magnetic resonance，relative permeability experiment and spontaneous imbibition experiment. At the same time，the performance of oil-displacing agent was compared with that of conventional sulfonate surfactant. The results showed that the average particle size of the nanoemulsion oil-displacing agent was 60 nm. When the mass fraction of the nanoemulsion oil-displacing agent increased，the surface tension of solution and oil-water interfacial tension gradually decreased. When the dosage of oil-displacing agent was 0.2%，the oil-water interfacial tension could reach 2.94×10^-3 mN/m，showing good interfacial activity. At the same time，it could change the core surface from lipophilicity to hydrophilicity，realizing wetting reversal. When the dosage of nanoemulsion oil-displacing agent was 0.2%，the emulsification efficiency to crude oil could reach 98% . The nanoemulsion oil-displacing agent had excellent temperature resistance and salt resistance. The static imbibition could increase oil recovery by more than 30 percentage points. The application of fracturing flooding in Xinjiang oilfield and water injection huff and puff in old wells showed that the nano imbibition flooding technology had better stimulation effect than conventional flooding technology. When the liquid production was not much different，the flowback rate was lower，while the oil production was higher. The oil displacement replacement effect was better.