The scaling of pipelines and storage tanks in Zhenyuan oilfield is very serious，and there are no effective anti-scaling measures. Firstly，the water types of two water samples in He 53 and Yan 116 in Fangshan operation area of Zhenyuan oilfield were analyzed，and then the scaling trend of mixed water samples was predicted by using the scaling prediction software OLI ScaleChem， which was verified by indoor experiments. Carboxymethylated inulin calcium carbonate （CaCO₃） scale inhibitor CMI，and strontium sulfate（SrSO₄）scale inhibitor P（MA/MMA）was prepared. The anti-scaling performance of the P（MA/MMA）and CMI on mixed water was studied，and its anti-scaling machine was analyzed. Results showed that there were lots of scaling ions in He 53 and Yan 116 water in Fangshan of Zhenyuan oilfield，and there were scaling tendency when they are mixed. Prediction results showed that when the volume ratio of He 53 to yan116 water was 8∶2，the scale amount was as high as 587 mg/L，and the scale types were CaCO₃ and SrSO₄. The experimental results were basically consistent with the predicted results. The scale inhibition rate of compound scale inhibitor CQ-SI，the mass ratio of CMI to P（MA/MMA）bening of 4∶6，could be as high as 93.5% when the dosage was 150 mg/L. CQ-SI inhibits the formation of scale by forming chelates with scaling cations，and plays an excellent anti-scaling effect by dispersing and separating scale samples.