The physical properties of the reservoir in the Bohai LD5-2 oilfield are characteristic of high permeability and strong heterogeneity. Long-term water flood development has further exacerbated heterogeneity between reservoirs. It is urgent to take flood control measures to realize deep fluid flow diversion. In this article，profile control and displacement were tested for injection pressure. The characteristics of LD5-2 reservoir were taken as the research object. The indoor three-tube parallel experiment was used to study the effect of injection pressure on the liquid absorption profile of the reservoir. The test results showed that microsphere particles are susceptible to stagnate on the end face of the core injection end，which caused the injection pressure to be "virtually high"，as a result，the liquid flow diverting effect was eventually weakened. Compared with microsphere-based flooding agents，polymer gel-based profile-controlling agents had a stronger injection capacity，and were more likely to enter deep cores and cause retention. The added seepage resistance and injection pressure increased significantly. With the increase of injection pressure， the liquid absorption of the middle and low permeability layers increased，the additional seepage resistance increased due to the retention effect，and the liquid flow diverting effect became worse. Therefore，adopting a reasonable injection pressure could help improve profile and flood control flow diverting effect. It was recommended to carry out the liquid absorption profile test of the injection well before implementing the profile adjustment measures at the mine to determine the maximum injection pressure or injection speed of the agent.