In order to make oleic acid evenly distributed in cement and prepare the hydrophilic cement material，the carrier quartz sand was modified by the hydrophobic material oleic acid，and OA-1 cement was obtained by introducing the modified quartz sand， and the overall wettability and compressive strength of cement test block was tested. At the same time，it was compared with OA-2 and OA-3 cement prepared by the direct addition of oleic acid and the dissolution of oleic acid with isopropanol，respectively. The microstructure and chemical composition of hydrophobic cement materials were characterized by SEM and XRD. The results showed that the average value of the contact angle of water on the OA-1 cement with oleic acid content of 5% could reach up to 145.18 °，indicating that the OA-1 cement had best hydrophobic effect. The compressive strength of the OA-I cement after curing for 3 days was greater than 21 MPa. Compared with that of blank cement，the water permeability of the OA-1 cement increased obviously，the average change rate was 77.87%，while the oil permeability of the OA-1 cement decreased obviously，the average change rate was 32.14%. OA-1 cement had selective water plugging effect and could achieve the purpose of oil stabilization and water control. Using quartz sand as a carrier，the oleic acid was wrapped in the surface of quartz sand without solvents，a uniform distribution of oleic acid could be achieved in the cement，thereby obtaining hydrophobic well cement.