Aiming at the problems of low sweep coefficient and low oil-washing efficiency of steam flooding for heavy oil，a high-temperature-resistant channeling plugging agent was prepared with petroleum resin particle， anionic surfactants and water-soluble high molecular polymer. The carboxylate surfactant and the sulfonate surfactant were compounded with a mass ratio of 1.5∶1 to obtain oil-washing agent. The compound profile-control and oil displacement technology of channeling plugging agent and oil-washing agent was investigated by physical simulation experiment. The injection and plugging properties of channeling plugging agent，as well as the ability of the compound profile-control and oil displacement system to improve the recovery of steam flooding were investigated. The results showed that the channeling plugging agent had good injection and plugging properties，and had good erosion resistance at a high temperature of 250℃. The channeling plugging agent had better injection performance for the core with the permeability greater than 3.0 μm2. The plugging rate could be maintained above 90% for the core with the permeability about 5.0 μm2，and the reduction of plugging rate was less than 2% after flooded 20 PV steam at 250°C. The oil-washing agent could reduce the oil-water interfacial tension to 10-3 mN/m，and the oil-washing efficiency at 90—250℃ was greater than 40%. The use of oil-washing agent alone in steam flooding could only increase the recovery by 14%，while the use of channeling plugging agent and oil-washing agent compound system could increase the recovery by 26%. The combination of channeling plugging agent and oil-washing agent in steam flooding could effectively block the steam channeling，increase oil displacement efficiency，and improve the development effect of steam flooding in heavy oil reservoir.