After CO2 was injected into the formation，it dissolved in formation water and formed carbonic acid. Various chemicalreactions occurred between carbonic acid and the formation rocks. The influence and mechanism of the reaction on reservoir physical properties were analyzed，which was of great significance for CO2 flooding in low permeability，ultra-low permeability and tight reservoirs. By analyzing the reaction characteristics and mechanisms between CO2，formation water and main single minerals，complex minerals of rock，the impacts and mechanisms of physical parameters such as porosity，permeability and wettability of rock after carbonation were reviewed. The physical and chemical interactions between CO2，formation water and rock minerals of tight reservoir would affect the physical properties of reservoir，which would provide some idea for the improvement of displacement efficiency in low permeability，ultra-low permeability and tight reservoir .