The low pressure tight gas reservoir is characteristic of low permeability，low porosity and low pressure coefficient. The problem of water sensitivity damage caused by fracturing fluid invasion is widespread in the low pressure tight gas reservoir. In order to reduce the damage of fracturing fluid to reservoir and increase the flowback rate of fracturing fluid，the slick water system with low surface tension was selected，composed of 0.15% drag reducer XY-205，0.1% clean up additive XY-120 and 0.2% antiswelling agent XY-63. The drag reducing rate，anti-swelling rate and core damage performance of the slick water were also investigated，and the slick water had been put into field uses. The result showed that the surface tension of the slick water was 20.12 mN/m and the interfacial tension between the slick water system and kerosene was 1.52 mN/m，The drag reduction rate of the slick water system was up to 70.58%，and the antiswelling ratio of the core of HG-01 well in Wangfu block was 90%. The core damage caused by slick water was as low as 14.46%. The application of slick water in 3 wells of low pressure tight gas reservoir showed that the fracturing operation was successful，the gas breakthrough rate was fast after fracturing，the flowback rate of slick water was 61%，and the gas came out after 4 hours of running slick water. The application of low surface tension slick water in low pressure tight gas reservoir had achieved good results.