Aiming at the fact that there were few species of oil soluble tracer used in oilfield and according to the properties of organofluorine compound with stability and high sensitivity， ethyl 4-fluorobenzoate（EB-F）was synthesized by thionyl chloride method and concentrated sulfuric acid catalysis method. The structure of the product was characterized by 1H NMR and mass spectrometry. The solubility of EB-F in water and kerosene was researched through chromatographic peak area which detected by HPLC. And the detection limit of EB-F concentration by GC-MS instrument was determined by the establishment of standard curve. The results showed that the product yield of thionyl chloride method and concentrated sulfuric acid catalysis method was about 86%. Compared with thionyl chloride method， concentrated sulfuric acid catalysis method was easier to operate， had lower cost and less pollution to environment， and was more suitable for industrial production. EB-F was soluble in oil and slightly soluble in water. The solubility in kerosene and water was 90 and 0.051 g/L respectively， and the oil-water partition ratio was 338. Trace amount of EB-F acetonitrile solution could be detected by GC-MS with 0.1×10^-3—50×10^-3 mg/L linear range of standard curve， 0.9984 R²， 4.1% RSD， and 1.5×10^-6mg/L minimum detection limit