The depth of Xushen gas field is greater than or equal to 3000 m，the well temperature is less than or equal to（le） 150 ℃ ，meanwhile，the climate character is long wintertime and low temperature. Aiming at these characteristics，the anionic surfactant palmitamide sulfobutyrate disodium （ASB-16A） was synthesized using maleic anhydride，cetamide and anhydrous sodium sulfite by two steps of amidation and sulfonation reaction. ASB-16A was mixed with foaming agent lauryl-glucoside （APG1214），antifreeze ethanol，and deionized water to prepare a bubble agent （CYY-1） with cold and high temperature resistance. The foam performance，high temperature resistance，low temperature stability and compatibility with formation water of CYY-1 were evaluated. Finally，CYY-1 was applied in Xushen gas field. The results showed that the optimum formula of CYY-1 was obtained as follows：10% ASB-16A，10% APG1214，44% ethanol，and deionized water. CYY-1 showed better foaming and steady blebbing properties. At 80 ℃，1.25% CYY-1 solution had an initial foam height of 150 mm，a foam height of 150 mm and 75 mm for 3 min and 5 min standing time，respectively，and a liquid volume of 1100 mL. The aging under weak base conditions， such as 8.5 pH value，150 ℃ and 24 hours，had little effect on the foam performance of CYY-1. The stability at low temperature of CYY-1 was better than that of commonly used low temperature bubble agent. After freezing at -35 ℃ for 7 d，CYY-1 became cloudy. But it could still flow in the pipeline，which met the requirements of automatic filling of device. The compatibility of CYY-1 with formation water was good. 0.5% —10.0% solution was still clear and transparent after standing for 48 hours at room temperature，so automatic bubble filling could be implemented. Two wells were tested in the field. The daily gas production of one well increased from 2.46×10⁴m³ to 3.07×10⁴m³. Meanwhile，the daily water yield decreased from 5.77 m³ to 3.70 m³. Stable carrying water production was achieved. CYY-1 was suitable for foam drainage gas production of well temperature le 150 ℃，salinity le 16 g/ L and pH value of 8.5.