For hydraulic fracturing in low-pressure strong hydrophilic tight gas reservoirs，it is necessary to evaluate the influence of the carrier and the usage environment on the performance of the anti-water blocking agent，and to make sure the anti-water blocking agent performs its proper function. Three different types of surfactants，including fluorocarbon anionic surfactant FCY137，fluorocarbon nonionic surfactant FCF102 and self-developed nano FC-ST，had been studied to reduce surface tension and change wettability. By comparing the performance of the solution under different viscosity，APS dosage，mineralization，and pH value，the best anti-water blocking agent were selected，and the waterproof locking capability was evaluated in fracturing fluid， through self-absorbing experiments，adsorption performance experiments sur factant and penetration rate recovery experiments. The results showed that the fluorocarbon anionic surfactant FCY137，fluorocarbon nonionic surfactant FCF102 and nano FC-ST could significantly reduce the surface tension，increase contact angle，effectively reduce the capillary force under the conventional indoor conditions. The nano-FC-ST could maintain stable performance in the fracturing gel-breaking fluid under the condition that the viscosity was less than 4 mPa·s，the temperature was below 120 ℃，APS dosage was 0.5 g/L，the mineralization of water was 1× 105 mg/L and pH value was lower than 11. The performances of the anti-water blocking agent nano surfactant FC-ST met the needs of common low-pressure strong hydrophilic tight gas reservoirs，and it was better than fluorocarbon anionic surfactant FCY137 and fluorocarbon nonionic surfactant FCF102. The slick water of nano FC-ST fracturing fluid could significantly reduce the capillary force，effectively reduce water intrusion，and reduce adsorption in the near well zone. It had a permeability recovery rate of more than 50%，compared with conventional anti-water blocking agent，cleanup additive，the performance was less affected by the carrier and the environment，the performance of the water blockage prevention was remarkable.