In view of the problems of poor acid resistance，complicated removal process and high cost of temporary plugging agent used in acid fracturing of carbonate reservoir，a kind of degradable gel temporary plugging agent with micro-expansion（WDS）for acid fracturing was prepared through aqueous radical polymerization method by using self-made quaternary ammonium ester （JD-1）as cross-linking agent. The degradation performance，plugging performance and reservoir damage of WDS were studied. Finally it was applied in HY well. The results showed that WDS was first micro-expansion and then degradation in HCl solution or aqueous solutions with different salinity. The complete degradation time of WDS in 10% HCl solution reduced from 78 h to 45 h when the temperature rose from 70 ℃ to 120 ℃ . When the mass fraction of HCl increased from 3% to 20%，the complete degradation time of WDS at 90 ℃ shortened from 75 h to 48 h. The higher the salt concentration，the longer the complete degradation time of WDS was. According to the results of core displacement experiment，with increasing injection of WDS and decreasing fracture width，the peak value of temporary plugging pressure increased，while the time reaching the maximum temporary plugging pressure reduced. In addition，WDS was less harmful to the core. The permeability recovery value of core was more than 90%. After using WDS in field application，the oil pressure was increased by 10 MPa，indicating remarkable effect of temporary plugging.