In the foam drainage and gas recovery process，it is difficult to achieve controllable defoaming after the foam reaches earth surface. In order to obtain a foam discharge system with both stability and responsiveness，and clarify the applicability in inorganic salt and oil phase environments，sodium dodecyl sulfate（SLS），sodium dodecyl sulfate（SDS）and sodium dodecyl benzene sulfonate（SDBS）were compounded with N-dodecyl-N，N-dimethyl tertiary amine（C₁₂A），respectively. The foam property of the compound solution and the effect of inorganic salt and oil on the compound system were studied. For the SLS/C₁₂A and SDS/ C₁₂A compound systems with better foam property，CO₂ response defoaming and N₂ heating re-foaming experiments were carried out，and the response mechanism of the compound foam was analyzed. The results showed that the foam property of SLS/C₁₂A compound system was the best，and the foam stability of SDBS/C₁₂A was the worst. SLS/C₁₂A compound system had strong salt tolerance，and SDS/C₁₂A compound system had significant oil resistance. Both compound systems showed good responsiveness and reversibility. The response mechanism was analyzed by the change of solution morphology and surface tension after defoaming. The protonated C₁₂A electrostatically attracted surfactant to form a complex，which precipitated from the solution. The surface activity of the solution was reduced and the breakage of the foam was accelerated. It had certain guiding significance for the selection of surfactant system in oil and gas fields with different environments.