The poor dissolution of hydrophobically associating polymers caused by the interactions of hydrophobes restricts their popularization and application on oilfields. Irreversible viscosity loss of polymer solution will inevitably occur through the current physical accelerated dissolution modes. Based on the inclusion of cyclodextrins and hydrophobes，cyclodextrin was added in the dissolution process of associating polymer，and the effects of cyclodextrin on the solubility and rheology of hydrophobic associating polymer were studied. The results showed that the inclusion of hydrophobe by cyclodextrin accelerated the dissolution of associating polymer without the loss of polymer solution viscosity. The inclusion of cyclodextrin on hydrophobe improved the interaction between associating polymer and solvent. As the molar ratio of cyclodextrin to hydrophobic group increased，the dissolution time of hydrophobically associating polymer decreased exponentially. Utilizing the competitive inclusion properties of cyclodextrin inclusion complex，the rheological properties of associating polymer solution could be completely restored by adding an appropriate amount of nonionic surfactant with stronger affinity to cyclodextrin.