A reversal wetting multi-effect additive（PA-VERT）was proposed in the paper, and the interfacial activity, wetting reversal performance, cleanup ability, waterproof damage capability and oil-washing ability of PA-VERT were evaluated through the measurements of the oil-water interfacial tension，wetting angle and the physical model experiments. Experimental results showed that the PA-VERT had excellent interfacial activity and could reduce the oil-water interfacial tension to 10^-2mN/m order of magnitude. The carbonate rock surface could be changed from oil-wet to water-wet with the treatment of the 1%PA-VERT solution. It could also significantly reduce the water influx rate at the constant pressure, as well as the pressure of oil driving water，which could effectively relieve water blocking damage，so it had high cleanup rate and strong ability of preventing water-damage; Besides， the additive has strong oil-washing power，and the increase of the temperature was beneficial to improve its capability of washing oil.