A tan drilling fluid lubricant BZ-BL was synthesized using waste animal/plant oil, ethanolamine, p-toluene sulfonic acid, hydrogen peroxide and white oil as raw material. The density, freezing point and fluorescence grade of lubricant was 0.9 g/cm³, -15℃ and 3, respectively. The optimum synthesis condition of lubricant was obtained as follows: 7% ethanol amine, 5% p-toluene sulfonic acid, 135—140℃ reaction temperature and 4 h reaction time. The performance test results showed that the reduced rate of lubricating coefficient of 4% brine and saturation brine mud was 76.9% and 67.4% respectively, which indicated good salt resistance, and the temperature resistance was up to 180℃. The effects of BZ-BL on rheological property and filtration property of polymer, silicate-based and potassium-based mud were small. The application of BZ-BL in more than 10 wells on site showed that the lubricant?had good lubricating property and good compatibility with drilling fluid additives. It was friendly to?the environment, which could be used at deep, highly-deviated, horizontal wells, and exploration and development of environmental sensitive region.