Alkali/surfactant/polymer (ASP) flooding can enhance oil recovery greatly, but the scaling problem restricts its large-scale application. The experiments were performed on reservoir rocks in Daqing Lamadian Oilfield and ASP system, visual research on rock structure after alkali flooding and research on alkaline driving agent flowing property were carried out in this paper. The microscopic experiments results showed that, alkali mainly dissolved clay minerals and had little impact on feldspar framework. The flow experiments results showed that in produced fluid, the concentrations of calcium ion and magnesium ion were low and had little impact on the core penetration, the concentration of silicon ion was high and deposition easily during migration would form a large of silicone scale in layer and production systems. Further analysis of the results showed that the damage of ASP flooding to the reservoir rock became severer as alkali concentration increasing, both surfactant and polymer could reduce dissolution, however, the effect of the former was weaker.