according to the need of enhancement of oil recovery after polymer flooding,the multiple profile control and displacement system combined by gel microsphere,cross-linking agent and high effective displacement agent was screened,and the profile control displacement experiments after polymer flooding were carried out by injecting the single system,namely,50 mg/L(or 100 mg/L)cross-linking agent or 2000 mg/L cationic gel microspheres,binary system,composed of 100 mg/L cationic gel microspheres and 2000 mg/L cross-linking agent,and ternary system,composed of 0.4 PV×2000 mg/L gel microsphere,0.3 PV×100 mg/L cross-linking agent and 0.4 PV×2000 mg/L high effective displacement.The results showed that,when the injection volume was 1 PV,the binary injection system was better than single injection system.The injection breakthrough pressure showed a marked increase after binary system injection,being of about 3 MPa,which indicated that the binary system could effectively block the medium and high permeability pore by using the residual polymer in the core.The enhancement of oil recovery of the ternary system was 22.82% based on the water flooding,oil recovery being of 39.65%,and polymer flooding,enhancement of oil recovery being 18.38%.The injecting pressure during water flooding and polymer flooding was lower;with the injection of the ternary system,the pressure increased rapidly;and the pressure remained at range of 2 MPa during the following water injection,which was lower than that of the binary system.As a result,the injection of the ternary system after polymer flooding could not only block the high permeable layers and channels,but also take full use of medium and low permeability layers.